Comparing Outcomes Between Vascularized Lymph Node Transfer and Lymphovenous Anastomosis in the Primary Lymphedema

2.50
Hdl Handle:
http://hdl.handle.net/10755/621818
Category:
Full-text
Format:
Text-based Document
Type:
Poster
Level of Evidence:
N/A
Research Approach:
N/A
Title:
Comparing Outcomes Between Vascularized Lymph Node Transfer and Lymphovenous Anastomosis in the Primary Lymphedema
Author(s):
Lin, Chia Yu; Liu, Hsueh-Erh
Lead Author STTI Affiliation:
Non-member
Author Details:
Chia Yu Lin, MS, RN, Professional Experience: 1997-2002, Clinic practice training --Chang Gung Memorial Hospital, Taoyuan 2003-2006, Clinic staff--Chang Gung Memorial Hospital, Taoyuan 2008-2014, Research Assistant--Chang Gung Memorial Hospital, Taoyuan 2014-Present, Coordinator--Chang Gung Memorial Hospital, Taoyuan Author Summary: Having obtained MS degree, Chia-Yu Lin completed Clinic research training at Chang Gung University. Chia-Yu’s major clinical practice are breast reconstruction and lymphedema microsurgery. Her research focuses are on vascularized lymph node flap transfer for lymphedema and quality of life.
Abstract:

Purpose:

Primary lymphedema is a devastating, debilitating disease. Much of the current treatment options demonstrate evidence in the treatment of secondary lymphedema. This study is to investigate the outcomes between vascularized lymph node (VLNT) transfers and lymphovenous anastomosis (LVA) in the treatment of primary lymphedema.

Methods:

A total of 17 patients were recruited to the study with a total of 19 lower limbs with primary lymphedema at Chang Gung Memorial Hospital. All patients reported a non-hereditary occurrence of lymphedema history that originated at birth. All patients were treated with either VLNT or LVA. Postoperative quality of life and serial circumferential limb measurements were compared. Group comparisons were performed using Mann-Whitney U test for circumference comparisons, and the Wilcoxon test for pre and postoperative group comparisons.This study was approved by the Institutional Review Board (IRB) at Chang Gung Memorial Hospital and performed in accordance with the Helsinki Declaration ethical standards.

Results:

15 limbs received VLNTs and had an average of 3.8cm reduction above knee, 3.6cm below knee and 4cm above ankle. An average total reduction was 3.7cm. 4 limbs received LVA treatment and had an average of 1.3cm reduction AK, 3.0cm BK and 1.5cm AA, giving an average total reduction of 1.9cm. Patients in the VLNT group had an average drop from 5.2 episodes preoperatively to 0.1 episodes postoperatively. Patients in the LVA group reported an average reduction in cellulitic episodes from 5 preoperatively to 0.8 postoperatively. In the VLNT group, an average significant improvement in quality of life was noted by 2.5 points. In the LVA group, an average improvement in the quality of life score was seen by 2 points.

Conclusion:

In conclusion, primary lymphedema can be treated adequately with improvements in both functional and quality of life outcomes if treatment options are chosen correctly. VLNT when used in severe cases of lymphedema, can provide greater relief with more impactful outcomes in both functional restoration and quality of life outcomes.

Keywords:
lymphovenous anastomosis; primary lymphedema; vascularized lymph node transfer
Repository Posting Date:
13-Jul-2017
Date of Publication:
13-Jul-2017
Other Identifiers:
INRC17PST
Conference Date:
2017
Conference Name:
28th International Nursing Research Congress
Conference Host:
Sigma Theta Tau International
Conference Location:
Dublin, Ireland
Description:
Event Theme: Influencing Global Health Through the Advancement of Nursing Scholarship

Full metadata record

DC FieldValue Language
dc.language.isoen_USen
dc.type.categoryFull-texten
dc.formatText-based Documenten
dc.typePosteren
dc.evidence.levelN/Aen
dc.research.approachN/Aen
dc.titleComparing Outcomes Between Vascularized Lymph Node Transfer and Lymphovenous Anastomosis in the Primary Lymphedemaen_US
dc.contributor.authorLin, Chia Yuen
dc.contributor.authorLiu, Hsueh-Erhen
dc.contributor.departmentNon-memberen
dc.author.detailsChia Yu Lin, MS, RN, Professional Experience: 1997-2002, Clinic practice training --Chang Gung Memorial Hospital, Taoyuan 2003-2006, Clinic staff--Chang Gung Memorial Hospital, Taoyuan 2008-2014, Research Assistant--Chang Gung Memorial Hospital, Taoyuan 2014-Present, Coordinator--Chang Gung Memorial Hospital, Taoyuan Author Summary: Having obtained MS degree, Chia-Yu Lin completed Clinic research training at Chang Gung University. Chia-Yu’s major clinical practice are breast reconstruction and lymphedema microsurgery. Her research focuses are on vascularized lymph node flap transfer for lymphedema and quality of life.en
dc.identifier.urihttp://hdl.handle.net/10755/621818-
dc.description.abstract<p><strong>Purpose:</strong></p> <p>Primary lymphedema is a devastating, debilitating disease. Much of the current treatment options demonstrate evidence in the treatment of secondary lymphedema. This study is to investigate the outcomes between vascularized lymph node (VLNT) transfers and lymphovenous anastomosis (LVA) in the treatment of primary lymphedema.</p> <p><strong>Methods:</strong></p> <p>A total of 17 patients were recruited to the study with a total of 19 lower limbs with primary lymphedema at Chang Gung Memorial Hospital. All patients reported a non-hereditary occurrence of lymphedema history that originated at birth. All patients were treated with either VLNT or LVA. Postoperative quality of life and serial circumferential limb measurements were compared. Group comparisons were performed using Mann-Whitney U test for circumference comparisons, and the Wilcoxon test for pre and postoperative group comparisons.This study was approved by the Institutional Review Board (IRB) at Chang Gung Memorial Hospital and performed in accordance with the Helsinki Declaration ethical standards.</p> <p><strong>Results:</strong></p> <p>15 limbs received VLNTs and had an average of 3.8cm reduction above knee, 3.6cm below knee and 4cm above ankle. An average total reduction was 3.7cm. 4 limbs received LVA treatment and had an average of 1.3cm reduction AK, 3.0cm BK and 1.5cm AA, giving an average total reduction of 1.9cm. Patients in the VLNT group had an average drop from 5.2 episodes preoperatively to 0.1 episodes postoperatively. Patients in the LVA group reported an average reduction in cellulitic episodes from 5 preoperatively to 0.8 postoperatively. In the VLNT group, an average significant improvement in quality of life was noted by 2.5 points. In the LVA group, an average improvement in the quality of life score was seen by 2 points.</p> <p><strong>Conclusion:</strong></p> <p>In conclusion, primary lymphedema can be treated adequately with improvements in both functional and quality of life outcomes if treatment options are chosen correctly. VLNT when used in severe cases of lymphedema, can provide greater relief with more impactful outcomes in both functional restoration and quality of life outcomes.</p>en
dc.subjectlymphovenous anastomosisen
dc.subjectprimary lymphedemaen
dc.subjectvascularized lymph node transferen
dc.date.available2017-07-13T15:37:15Z-
dc.date.issued2017-07-13-
dc.date.accessioned2017-07-13T15:37:15Z-
dc.conference.date2017en
dc.conference.name28th International Nursing Research Congressen
dc.conference.hostSigma Theta Tau Internationalen
dc.conference.locationDublin, Irelanden
dc.descriptionEvent Theme: Influencing Global Health Through the Advancement of Nursing Scholarshipen
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