A Longitudinal Study of Body Weight Loss in Patients Receiving Radiotherapy for Head/Neck Cancers

2.50
Hdl Handle:
http://hdl.handle.net/10755/621902
Category:
Full-text
Format:
Text-based Document
Type:
Poster
Level of Evidence:
N/A
Research Approach:
N/A
Title:
A Longitudinal Study of Body Weight Loss in Patients Receiving Radiotherapy for Head/Neck Cancers
Author(s):
Lee, Shu-Chiung; Wang, Tsae-Jyy
Lead Author STTI Affiliation:
Non-member
Author Details:
Shu-Chiung Lee, MSN, RN, Professional Experience: 2010-present --head nurse of Taipei Veterans General Hospital,Taiwan 2008-present --instructor of National Taipei University of Nursing and health Sciences 2008-present --Administrative project reviewer of Taiwan Nurses Association. Author Summary: Ms. Lee is engaged in clinical nursing for 30 years, specializing in cardiovascular disease and head and neck cancer care.Provide nursing students clinical practice teaching.
Abstract:

Purpose: 1. to describe body weight change over time in patients receiving RT for head neck cancer.

2. to explore the influence of mucositis and nutritional support on weight change over time.

 

Methods:  The study uses a longitudinal design. A convenient sample of 101 H&NC patients scheduled for RT was recruited from a medical center in Taiwan. Data on patients’ demographics and clinical variables were collected prior to RT. Body weight and mucositis were measured repeatedly at baseline (T1), one month (T2), the completion of radiotherapy (T3), and one month after completing radiotherapy (T4).

Results:

The mean age of the sample was 54.3 (SD=10.8). Majority of the patients were male (n = 87), married (n = 80), and had a middle school (n = 30) education level. Thirty-seven patients had oral cancer, 29 had nasopharyngeal cancer, 23 had oropharynx cancer, and 12 had pharynx cancer. Their cancer stages were 11 in stage I or II, 23 in stage III, and 67 in stage IV. The average body weight was 69.4 Kg (SD = 13.2) at T1, 66.3 (SD = 12.0) at T2, 64.5 (SD = 11.9) at T3, and 63.4 (SD =10.7) at T4. Results of GEE showed a significant time effect [F =2802.6, P<.001] on body weight. As for the parameter estimates, the patients’ body weight dropped from the baseline by 5.96 kg at T4, 4.82 kg at T3, and 3.09 kg at T2. Results of GEE also showed a significant main effect of mucositis and interaction effects of nutritional support by time on body weight after controlling for the patients’ height, age, and the dose of radiation. Patients with a higher grade of mucositis had a lower body weight. The changes of body weight over time were significantly different among patients with different types of nutritional support. Those who had oral intake during the entire course of RT or had enteral tube feeding part-way through the course of RT had more weight loss than those who received enteral tube feeding during the course of RT.

Conclusion:

The results of the study supported that H&NC patients are at a great risk for body weight loss while receiving RT, especially for those with severe mucositis. Enteral tube feeding may provide better nutritional support than oral intake in this population. However, more studies are needed to verify this finding.

Keywords:
body weight; mucositis; radiotherapy
Repository Posting Date:
18-Jul-2017
Date of Publication:
18-Jul-2017
Other Identifiers:
INRC17PST628
Conference Date:
2017
Conference Name:
28th International Nursing Research Congress
Conference Host:
Sigma Theta Tau International
Conference Location:
Dublin, Ireland
Description:
Event Theme: Influencing Global Health Through the Advancement of Nursing Scholarship

Full metadata record

DC FieldValue Language
dc.language.isoen_USen
dc.type.categoryFull-texten
dc.formatText-based Documenten
dc.typePosteren
dc.evidence.levelN/Aen
dc.research.approachN/Aen
dc.titleA Longitudinal Study of Body Weight Loss in Patients Receiving Radiotherapy for Head/Neck Cancersen_US
dc.contributor.authorLee, Shu-Chiungen
dc.contributor.authorWang, Tsae-Jyyen
dc.contributor.departmentNon-memberen
dc.author.detailsShu-Chiung Lee, MSN, RN, Professional Experience: 2010-present --head nurse of Taipei Veterans General Hospital,Taiwan 2008-present --instructor of National Taipei University of Nursing and health Sciences 2008-present --Administrative project reviewer of Taiwan Nurses Association. Author Summary: Ms. Lee is engaged in clinical nursing for 30 years, specializing in cardiovascular disease and head and neck cancer care.Provide nursing students clinical practice teaching.en
dc.identifier.urihttp://hdl.handle.net/10755/621902-
dc.description.abstract<p><strong>Purpose: </strong><span>1. to describe body weight change over time in patients receiving RT for head neck cancer.</span></p> <p>2. to explore the influence of mucositis and nutritional support on weight change over time.</p> <p> </p> <p><strong>Methods: </strong> The study uses a longitudinal design. A convenient sample of 101 H&NC patients scheduled for RT was recruited from a medical center in Taiwan. Data on patients’ demographics and clinical variables were collected prior to RT. Body weight and mucositis were measured repeatedly at baseline (T1), one month (T2), the completion of radiotherapy (T3), and one month after completing radiotherapy (T4).</p> <p><strong>Results:</strong></p> <p>The mean age of the sample was 54.3 (SD=10.8). Majority of the patients were male (n = 87), married (n = 80), and had a middle school (n = 30) education level. Thirty-seven patients had oral cancer, 29 had <em>nasopharyngeal cancer,</em> 23 had oropharynx cancer, and 12 had pharynx cancer. Their cancer stages were 11 in stage I or II, 23 in stage III, and 67 in stage IV. The average body weight was 69.4 Kg (SD = 13.2) at T1, 66.3 (SD = 12.0) at T2, 64.5 (SD = 11.9) at T3, and 63.4 (SD =10.7) at T4. Results of GEE showed a significant time effect [F =2802.6, P<.001] on body weight. As for the parameter estimates, the patients’ body weight dropped from the baseline by 5.96 kg at T4, 4.82 kg at T3, and 3.09 kg at T2. Results of GEE also showed a significant main effect of mucositis and interaction effects of nutritional support by time on body weight after controlling for the patients’ height, age, and the dose of radiation. Patients with a higher grade of mucositis had a lower body weight. The changes of body weight over time were significantly different among patients with different types of nutritional support. Those who had oral intake during the entire course of RT or had enteral tube feeding part-way through the course of RT had more weight loss than those who received enteral tube feeding during the course of RT.</p> <p><strong>Conclusion:</strong></p> <p>The results of the study supported that H&NC patients are at a great risk for body weight loss while receiving RT, especially for those with severe mucositis. Enteral tube feeding may provide better nutritional support than oral intake in this population. However, more studies are needed to verify this finding.</p>en
dc.subjectbody weighten
dc.subjectmucositisen
dc.subjectradiotherapyen
dc.date.available2017-07-18T17:29:23Z-
dc.date.issued2017-07-18-
dc.date.accessioned2017-07-18T17:29:23Z-
dc.conference.date2017en
dc.conference.name28th International Nursing Research Congressen
dc.conference.hostSigma Theta Tau Internationalen
dc.conference.locationDublin, Irelanden
dc.descriptionEvent Theme: Influencing Global Health Through the Advancement of Nursing Scholarshipen
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