Efficacy of Chlorhexidine Versus Listerine Perioperative Mouthwash in Preventing Ventilator-Acquired Pneumonia: An Integrative Review

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Hdl Handle:
http://hdl.handle.net/10755/624144
Category:
Full-text
Format:
Text-based Document
Type:
Other Graduate Paper
Level of Evidence:
Literature Review
Research Approach:
Translational Research/Evidence-based Practice
Title:
Efficacy of Chlorhexidine Versus Listerine Perioperative Mouthwash in Preventing Ventilator-Acquired Pneumonia: An Integrative Review
Author(s):
Clements, James Owen
Additional Author Information:
James O. Clements, DNAP, CRNA, james.clements@bryanhealthcollge.edu
Advisors:
Pecka, Shannon
Degree:
Doctoral – Other
Degree Year:
2018
Grantor:
Bryan College of Health Sciences
Abstract:

Objective: To compare the safety and efficacy of chlorhexidine versus Listerine in perioperative and intensive care settings in preventing ventilator-acquired pneumonia (VAP).

Methods: An integrative review using a keyword search was conducted in Cochrane, Cinahl, and Google Scholar databases. Data was collected regarding the efficacy of chlorhexidine and Listerine in preventing ventilator-acquired pneumonia, safety and side effect profiles, and in vivoin vitro secondary outcome measures.

Results: Chlorhexidine demonstrates superiority to Listerine in reducing ventilator-acquired pneumonia. Secondary in vivo tests including plaque and gingivitis reduction, and in vitro tests measuring the effect on bacterial loads, also favors chlorhexidine over Listerine. Chlorhexidine has shown to have significantly more side effects compared to Listerine.

Conclusions: Chlorhexidine is justifiably used in preventing ventilator-acquired pneumonia over Listerine. There is a gap in knowledge due to the lack of randomized-controlled trials utilizing Listerine in VAP bundles. Future research should focus on finding an alternative mouthwash to chlorhexidine that is equally effective at reducing VAP incidence, but lacks chlorhexidine’s undesirable side effect profile.

Keywords:
Listerine; ventilator-acquired pneumonia; VAP
CINAHL Headings:
Pneumonia, Ventilator-Associated--Prevention and Control; Mouthwashes; Dental Plaque--Prevention and Control; Chlorhexidine; Pneumonia, Ventilator-Associated; Dental Plaque
Repository Posting Date:
2018-05-11T18:22:34Z
Date of Publication:
2018-05-11

Full metadata record

DC FieldValue Language
dc.contributor.advisorPecka, Shannonen
dc.contributor.authorClements, James Owenen
dc.date.accessioned2018-05-11T18:22:34Z-
dc.date.available2018-05-11T18:22:34Z-
dc.date.issued2018-05-11-
dc.identifier.urihttp://hdl.handle.net/10755/624144-
dc.description.abstract<p><em>Objective: </em>To compare the safety and efficacy of chlorhexidine versus Listerine in perioperative and intensive care settings in preventing ventilator-acquired pneumonia (VAP).</p> <p><em>Methods: </em>An integrative review using a keyword search was conducted in Cochrane, Cinahl, and Google Scholar databases. Data was collected regarding the efficacy of chlorhexidine and Listerine in preventing ventilator-acquired pneumonia, safety and side effect profiles, and <em>in vivo</em><em>in vitro </em> secondary outcome measures. </p> <p><em>Results:</em> Chlorhexidine demonstrates superiority to Listerine in reducing ventilator-acquired pneumonia. Secondary <em>in vivo </em>tests including plaque and gingivitis reduction, and <em>in vitro </em>tests measuring the effect on bacterial loads, also favors chlorhexidine over Listerine. Chlorhexidine has shown to have significantly more side effects compared to Listerine.</p> <p><em>Conclusions: </em>Chlorhexidine is justifiably used in preventing ventilator-acquired pneumonia over Listerine. There is a gap in knowledge due to the lack of randomized-controlled trials utilizing Listerine in VAP bundles. Future research should focus on finding an alternative mouthwash to chlorhexidine that is equally effective at reducing VAP incidence, but lacks chlorhexidine’s undesirable side effect profile.</p>en
dc.formatText-based Documenten
dc.language.isoenen
dc.subjectListerineen
dc.subjectventilator-acquired pneumoniaen
dc.subjectVAPen
dc.titleEfficacy of Chlorhexidine Versus Listerine Perioperative Mouthwash in Preventing Ventilator-Acquired Pneumonia: An Integrative Reviewen
dc.typeOther Graduate Paperen
thesis.degree.grantorBryan College of Health Sciencesen
thesis.degree.levelDoctoral – Otheren
dc.primary-author.detailsJames O. Clements, DNAP, CRNA, james.clements@bryanhealthcollge.eduen
thesis.degree.year2018en
dc.type.categoryFull-texten
dc.evidence.levelLiterature Reviewen
dc.research.approachTranslational Research/Evidence-based Practiceen
dc.subject.cinahlPneumonia, Ventilator-Associated--Prevention and Controlen
dc.subject.cinahlMouthwashesen
dc.subject.cinahlDental Plaque--Prevention and Controlen
dc.subject.cinahlChlorhexidineen
dc.subject.cinahlPneumonia, Ventilator-Associateden
dc.subject.cinahlDental Plaqueen
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